Search results for "Basic Study"
showing 3 items of 3 documents
Enseñanza mutua en línea: una investigación piloto realizada con los estudiantes universitarios
2023
In academic year 2020-2021, a pilot research was carried out on distance peer teaching, which was hypothesized as effective tool to reduce some of the negative effects that distance teaching, imposed by the Coronavirus pandemic, caused among students enrolled in the first year of the three-year degree course in Educational Sciences at the University of Palermo during the academic year 2019-2020. Nineteen students attending the second year of this course, after having participated in a specific training activity (15 h), from March to June 2021 helped 35 fellow students to advance their careers by catching up as many first-year exams as possible through distance support. In July 2021, the gro…
L-carnitine protects C2C12 cells against mitochondrial superoxide overproduction and cell death.
2017
International audience; AIMTo identify and characterize the protective effect that L-carnitine exerted against an oxidative stress in C2C12 cells.METHODSMyoblastic C2C12 cells were treated with menadione, a vitamin K analog that engenders oxidative stress, and the protective effect of L-carnitine (a nutrient involved in fatty acid metabolism and the control of the oxidative process), was assessed by monitoring various parameters related to the oxidative stress, autophagy and cell death.RESULTSAssociated with its physiological function, a muscle cell metabolism is highly dependent on oxygen and may produce reactive oxygen species (ROS), especially under pathological conditions. High levels o…
Effects of asymmetric dimethylarginine on renal arteries in portal hypertension and cirrhosis
2016
AIM. To evaluate the effects of asymmetric dimethylarginine (ADMA) in renal arteries from portal hypertensive and cirrhotic rats. METHODS. Rat renal arteries from Sham (n = 15), pre-hepatic portal hypertension (PPVL; n = 15) and bile duct ligation and excision-induced cirrhosis (BDL; n = 15) were precontracted with norepinephrine, and additional contractions were induced with ADMA (10-6-10-3 mol/L), an endogenous inhibitor of nitric oxide (NO) synthase. Concentration-response curves to acetylcholine (1 × 10-9-3 × 10-6 mol/L) were determined in precontracted renal artery segments with norepinephrine in the absence and in the presence of ADMA. Kidneys were collected to determine the protein e…